Nog klein jakkalsies

Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system

PURPOSE It is still technically difficult to collect high purity cancer cells from tumor tissues, which contain noncancerous cells. We hypothesized that xenograft models of NOG mice expressing enhanced green fluorescent protein (eGFP), referred to as NOG-EGFP mice, may be useful for obtaining such high purity cancer cells for detailed molecular and cellular analyses. METHODS Pancreato-biliary...

Establishment of patient-derived cancer xenografts in immunodeficient NOG mice

Viable and stable human cancer cell lines and animal models combined with adequate clinical information are essential for future advances in cancer research and patient care. Conventional in vitro cancer cell lines are commonly available; however, they lack detailed information on the patient from which they originate, including disease phenotype and drug sensitivity. Patient-derived xenografts...

Klein Reduction

We obtain new results for consistent braneworld Kaluza-Klein reductions, showing how we can derive four-dimensional N = 2 gauged supergravity " localised on the AdS 4 brane " as an exact embedding in five-dimensional N = 4 gauged supergravity. Similarly, we obtain five-dimensional N = 2 gauged supergravity localised on an AdS 5 brane as a consistent Kaluza-Klein reduction from six-dimensional N...

Higher susceptibility of NOG mice to xenotransplanted tumors.

The purpose of tumorigenicity testing, as applied not only to cell substrates used for viral vaccine manufacture but also stem cells used for cell-based therapy, is to discriminate between cells that have the capacity to form tumors and cells that do not. Therefore, tumorigenicity testing is essential in assessing the safety of these biological materials. Recently developed NOD/Shi-scid IL2Rg(n...

WAVELET SOLUTIONS OF THE KLEIN-GORDON EQUATION